BDBM50102790 2-(2-Hydroxy-5-nitro-biphenyl-3-yl)-1H-indole-5-carboxamidine::CHEMBL94775
SMILES: NC(=N)c1ccc2[nH]c(cc2c1)-c1cc(cc(c1O)-c1ccccc1)[N+]([O-])=O
InChI Key: InChIKey=VGQFBYXDHFTAHX-UHFFFAOYSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Coagulation factor X (Homo sapiens (Human)) | BDBM50102790 (2-(2-Hydroxy-5-nitro-biphenyl-3-yl)-1H-indole-5-ca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity against human coagulation factor X | J Med Chem 44: 2753-71 (2001) BindingDB Entry DOI: 10.7270/Q2RX9BC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue-type plasminogen activator (Homo sapiens (Human)) | BDBM50102790 (2-(2-Hydroxy-5-nitro-biphenyl-3-yl)-1H-indole-5-ca...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA). | J Med Chem 44: 2753-71 (2001) BindingDB Entry DOI: 10.7270/Q2RX9BC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urokinase-type plasminogen activator (Homo sapiens (Human)) | BDBM50102790 (2-(2-Hydroxy-5-nitro-biphenyl-3-yl)-1H-indole-5-ca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals Inc. Curated by ChEMBL | Assay Description ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA). | J Med Chem 44: 2753-71 (2001) BindingDB Entry DOI: 10.7270/Q2RX9BC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-1 (Homo sapiens (Human)) | BDBM50102790 (2-(2-Hydroxy-5-nitro-biphenyl-3-yl)-1H-indole-5-ca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of Human Serine Protease Trypsin. | J Med Chem 44: 2753-71 (2001) BindingDB Entry DOI: 10.7270/Q2RX9BC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50102790 (2-(2-Hydroxy-5-nitro-biphenyl-3-yl)-1H-indole-5-ca...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of Human Serine Protease Thrombin. | J Med Chem 44: 2753-71 (2001) BindingDB Entry DOI: 10.7270/Q2RX9BC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50102790 (2-(2-Hydroxy-5-nitro-biphenyl-3-yl)-1H-indole-5-ca...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of Human Serine Protease Plasmin. | J Med Chem 44: 2753-71 (2001) BindingDB Entry DOI: 10.7270/Q2RX9BC7 | |||||||||||
More data for this Ligand-Target Pair |