BDBM50102853 CHEMBL3329632

SMILES: Cn1c2ncnc(N3CCC[C@@H](N)C3)c2n(Cc2ccccc2C#N)c1=O

InChI Key: InChIKey=FMKHFRGVEQUFSX-OAHLLOKOSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50102853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50102853 (CHEMBL3329632) Show SMILES Cn1c2ncnc(N3CCC[C@@H](N)C3)c2n(Cc2ccccc2C#N)c1=O |r| Show InChI InChI=1S/C19H21N7O/c1-24-17-16(18(23-12-22-17)25-8-4-7-15(21)11-25)26(19(24)27)10-14-6-3-2-5-13(14)9-20/h2-3,5-6,12,15H,4,7-8,10-11,21H2,1H3/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
XuanZhu Pharma Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4 pre-incubated with compound for 15 mins before substrate addition by luminescence assay				ACS Med Chem Lett 5: 921-6 (2014) Article DOI: 10.1021/ml5001905 BindingDB Entry DOI: 10.7270/Q2N29ZQM
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50102853 (CHEMBL3329632) Show SMILES Cn1c2ncnc(N3CCC[C@@H](N)C3)c2n(Cc2ccccc2C#N)c1=O |r| Show InChI InChI=1S/C19H21N7O/c1-24-17-16(18(23-12-22-17)25-8-4-7-15(21)11-25)26(19(24)27)10-14-6-3-2-5-13(14)9-20/h2-3,5-6,12,15H,4,7-8,10-11,21H2,1H3/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
XuanZhu Pharma Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP8 pre-incubated with compound for 15 mins before substrate addition by luminescence assay				ACS Med Chem Lett 5: 921-6 (2014) Article DOI: 10.1021/ml5001905 BindingDB Entry DOI: 10.7270/Q2N29ZQM
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50102853 (CHEMBL3329632) Show SMILES Cn1c2ncnc(N3CCC[C@@H](N)C3)c2n(Cc2ccccc2C#N)c1=O |r| Show InChI InChI=1S/C19H21N7O/c1-24-17-16(18(23-12-22-17)25-8-4-7-15(21)11-25)26(19(24)27)10-14-6-3-2-5-13(14)9-20/h2-3,5-6,12,15H,4,7-8,10-11,21H2,1H3/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
XuanZhu Pharma Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP9 pre-incubated with compound for 15 mins before substrate addition by luminescence assay				ACS Med Chem Lett 5: 921-6 (2014) Article DOI: 10.1021/ml5001905 BindingDB Entry DOI: 10.7270/Q2N29ZQM
					More data for this Ligand-Target Pair