BindingDB logo
myBDB logout

null

SMILES: ClC(Cn1ncc2c(Nc3ccccc3)nc(SC3CCCC3)nc12)c1ccccc1

InChI Key: InChIKey=PTJTVFVEJBDKRO-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102907   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50102907
PNG
(CHEMBL3394088)
Show SMILES ClC(Cn1ncc2c(Nc3ccccc3)nc(SC3CCCC3)nc12)c1ccccc1
Show InChI InChI=1S/C24H24ClN5S/c25-21(17-9-3-1-4-10-17)16-30-23-20(15-26-30)22(27-18-11-5-2-6-12-18)28-24(29-23)31-19-13-7-8-14-19/h1-6,9-12,15,19,21H,7-8,13-14,16H2,(H,27,28,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 120n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena Via Aldo Moro 2

Curated by ChEMBL


Assay Description
Inhibition of human recombinant src kinase using KVEKIGEGTYGVVYK as substrate by filter binding assay in presence of [gamma-32P]ATP

J Med Chem 58: 347-61 (2015)


Article DOI: 10.1021/jm5013159
BindingDB Entry DOI: 10.7270/Q2416ZTT
More data for this
Ligand-Target Pair