BDBM50103077 2-Piperazin-1-yl-1H-benzoimidazole::CHEMBL292066
SMILES: C1CN(CCN1)c1nc2ccccc2[nH]1
InChI Key: InChIKey=NZXGDKLTTHIYTB-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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5-hydroxytryptamine receptor 3A (Homo sapiens (Human)) | BDBM50103077 (2-Piperazin-1-yl-1H-benzoimidazole | CHEMBL292066) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Louisiana at Monroe Curated by ChEMBL | Assay Description Binding affinity of the compound against human 5-hydroxytryptamine 3A receptor | Bioorg Med Chem Lett 11: 2133-6 (2001) BindingDB Entry DOI: 10.7270/Q20G3JGG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM50103077 (2-Piperazin-1-yl-1H-benzoimidazole | CHEMBL292066) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonist | J Med Chem 41: 2029-39 (1998) Article DOI: 10.1021/jm970745o BindingDB Entry DOI: 10.7270/Q2CJ8H7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM50103077 (2-Piperazin-1-yl-1H-benzoimidazole | CHEMBL292066) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
FAES, S.A. Curated by ChEMBL | Assay Description In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortex | J Med Chem 40: 586-93 (1997) Article DOI: 10.1021/jm960442e BindingDB Entry DOI: 10.7270/Q2P271TB | |||||||||||
More data for this Ligand-Target Pair |