BDBM50103096 (R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methyl-pentanoic acid [3-methyl-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL66181
SMILES: CC(C)C[C@H](NC(=O)[C@H](CC(C)C)[C@H](C)N(O)C=O)C(=O)Nc1nccs1
InChI Key: InChIKey=WEQCLTHHZZNFDV-ZNMIVQPWSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50103096 ((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research and Development Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-9 | Bioorg Med Chem Lett 11: 2147-51 (2001) BindingDB Entry DOI: 10.7270/Q2QZ298V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human)) | BDBM50103096 ((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research and Development Curated by ChEMBL | Assay Description Inhibitionof Tumor necrosis factor alpha converting enzyme | Bioorg Med Chem Lett 11: 2147-51 (2001) BindingDB Entry DOI: 10.7270/Q2QZ298V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM50103096 ((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research and Development Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-3 | Bioorg Med Chem Lett 11: 2147-51 (2001) BindingDB Entry DOI: 10.7270/Q2QZ298V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interstitial collagenase (Homo sapiens (Human)) | BDBM50103096 ((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 97 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research and Development Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-1 | Bioorg Med Chem Lett 11: 2147-51 (2001) BindingDB Entry DOI: 10.7270/Q2QZ298V | |||||||||||
More data for this Ligand-Target Pair |