BDBM50103129 CHEMBL3394125

SMILES: OC(=O)\C=C/Sc1nc(c([nH]1)-c1ccnc(Nc2ccccc2)c1)-c1ccc(F)cc1

InChI Key: InChIKey=ARVSBTXGNYKBJK-QBFSEMIESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50103129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50103129 (CHEMBL3394125) Show SMILES OC(=O)\C=C/Sc1nc(c([nH]1)-c1ccnc(Nc2ccccc2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H17FN4O2S/c24-17-8-6-15(7-9-17)21-22(28-23(27-21)31-13-11-20(29)30)16-10-12-25-19(14-16)26-18-4-2-1-3-5-18/h1-14H,(H,25,26)(H,27,28)(H,29,30)/b13-11-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha (unknown origin) assessed as phosphorylation of ATF-2 by ELISA				J Med Chem 58: 443-56 (2015) Article DOI: 10.1021/jm501557a BindingDB Entry DOI: 10.7270/Q2RN39MX
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50103129 (CHEMBL3394125) Show SMILES OC(=O)\C=C/Sc1nc(c([nH]1)-c1ccnc(Nc2ccccc2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H17FN4O2S/c24-17-8-6-15(7-9-17)21-22(28-23(27-21)31-13-11-20(29)30)16-10-12-25-19(14-16)26-18-4-2-1-3-5-18/h1-14H,(H,25,26)(H,27,28)(H,29,30)/b13-11-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Inhibition of JNK3 (unknown origin) assessed as phosphorylation of ATF-2 by ELISA				J Med Chem 58: 443-56 (2015) Article DOI: 10.1021/jm501557a BindingDB Entry DOI: 10.7270/Q2RN39MX
					More data for this Ligand-Target Pair