BDBM50103162 CHEMBL68542::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-5-naphthalen-2-yl-benzamide

SMILES: COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)-c1ccc2ccccc2c1

InChI Key: InChIKey=PCSKPZLQCNGMCY-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103162   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50103162 (CHEMBL68542 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)-c1ccc2ccccc2c1 Show InChI InChI=1S/C31H27N3O5S/c1-21-16-26(25-10-9-23-7-3-4-8-24(23)17-25)18-29(31(35)33-36)30(21)34(20-22-6-5-15-32-19-22)40(37,38)28-13-11-27(39-2)12-14-28/h3-19,36H,20H2,1-2H3,(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	745	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of Matrix metalloprotease-1				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50103162 (CHEMBL68542 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)-c1ccc2ccccc2c1 Show InChI InChI=1S/C31H27N3O5S/c1-21-16-26(25-10-9-23-7-3-4-8-24(23)17-25)18-29(31(35)33-36)30(21)34(20-22-6-5-15-32-19-22)40(37,38)28-13-11-27(39-2)12-14-28/h3-19,36H,20H2,1-2H3,(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro ability to inhibit matrix metalloprotease-9.				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50103162 (CHEMBL68542 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)-c1ccc2ccccc2c1 Show InChI InChI=1S/C31H27N3O5S/c1-21-16-26(25-10-9-23-7-3-4-8-24(23)17-25)18-29(31(35)33-36)30(21)34(20-22-6-5-15-32-19-22)40(37,38)28-13-11-27(39-2)12-14-28/h3-19,36H,20H2,1-2H3,(H,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50103162 (CHEMBL68542 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)-c1ccc2ccccc2c1 Show InChI InChI=1S/C31H27N3O5S/c1-21-16-26(25-10-9-23-7-3-4-8-24(23)17-25)18-29(31(35)33-36)30(21)34(20-22-6-5-15-32-19-22)40(37,38)28-13-11-27(39-2)12-14-28/h3-19,36H,20H2,1-2H3,(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	194	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of TNF-alpha converting enzyme (TACE)				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair