BDBM50103373 CHEMBL3398189
SMILES: NCCCN(CCCCN(CCCN)C1c2ccccc2CCc2ccccc12)C1c2ccccc2CCc2ccccc12
InChI Key: InChIKey=AJXJWZFPYVJZEU-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trypanothione reductase (Trypanosoma cruzi) | BDBM50103373 (CHEMBL3398189) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 255 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Canisius College Curated by ChEMBL | Assay Description Inhibition of Trypanosoma cruzi trypanothione reductase assessed as reduction of trypanothione disulfide by spectrophotometrically | Bioorg Med Chem 23: 996-1010 (2015) BindingDB Entry DOI: 10.7270/Q27P9166 | |||||||||||
More data for this Ligand-Target Pair |