BDBM50103421 1,1-Dibutyl-6-chloro-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL321282
SMILES: CCCCC1(CCCC)NC(Cc2c1[nH]c1ccc(Cl)cc21)c1nc(c[nH]1)-c1ccccc1
InChI Key: InChIKey=DBLQQFZKWOTGKW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50103421 (1,1-Dibutyl-6-chloro-3-(4-phenyl-1H-imidazol-2-yl)...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype | J Med Chem 44: 2990-3000 (2001) BindingDB Entry DOI: 10.7270/Q2DB82JT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50103421 (1,1-Dibutyl-6-chloro-3-(4-phenyl-1H-imidazol-2-yl)...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibitory concentration required to inhibit SRIF-14 induced reduction of cAMP in CHO-K1 cells expressing the human sst3 receptor. | J Med Chem 44: 2990-3000 (2001) BindingDB Entry DOI: 10.7270/Q2DB82JT | |||||||||||
More data for this Ligand-Target Pair |