BDBM50103537 CHEMBL3357984

SMILES: CC1CN2C(C(C)O1)C1(Cc3cc4c(C)noc4c(Cl)c23)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=YUFDLDKPRBELKV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA Gyrase (Escherichia coli (strain K12))	BDBM50103537 (CHEMBL3357984) Show SMILES CC1CN2C(C(C)O1)C1(Cc3cc4c(C)noc4c(Cl)c23)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C19H19ClN4O5/c1-7-6-24-13-10(4-11-8(2)23-29-14(11)12(13)20)5-19(15(24)9(3)28-7)16(25)21-18(27)22-17(19)26/h4,7,9,15H,5-6H2,1-3H3,(H2,21,22,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase using fluorescence-tagged DNA by fluorescenct polarization assay				J Med Chem 57: 9078-95 (2014) BindingDB Entry DOI: 10.7270/Q2F76FB6
					More data for this Ligand-Target Pair