BDBM50103555 CHEMBL3358002

SMILES: C[C@@H]1CN(CCN1c1ncc(OCc2ccc(OS(C)(=O)=O)cc2F)cn1)c1nnc(o1)C(F)(F)F

InChI Key: InChIKey=UTOPRESBQKAWRB-GFCCVEGCSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50103555 (CHEMBL3358002) Show SMILES C[C@@H]1CN(CCN1c1ncc(OCc2ccc(OS(C)(=O)=O)cc2F)cn1)c1nnc(o1)C(F)(F)F |r| Show InChI InChI=1S/C20H20F4N6O5S/c1-12-10-29(19-28-27-17(34-19)20(22,23)24)5-6-30(12)18-25-8-15(9-26-18)33-11-13-3-4-14(7-16(13)21)35-36(2,31)32/h3-4,7-9,12H,5-6,10-11H2,1-2H3/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp based electrophysiology method				J Med Chem 57: 8984-98 (2014) BindingDB Entry DOI: 10.7270/Q29G5PK1
					More data for this Ligand-Target Pair
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50103555 (CHEMBL3358002) Show SMILES C[C@@H]1CN(CCN1c1ncc(OCc2ccc(OS(C)(=O)=O)cc2F)cn1)c1nnc(o1)C(F)(F)F |r| Show InChI InChI=1S/C20H20F4N6O5S/c1-12-10-29(19-28-27-17(34-19)20(22,23)24)5-6-30(12)18-25-8-15(9-26-18)33-11-13-3-4-14(7-16(13)21)35-36(2,31)32/h3-4,7-9,12H,5-6,10-11H2,1-2H3/t12-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assay				J Med Chem 57: 8984-98 (2014) BindingDB Entry DOI: 10.7270/Q29G5PK1
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Mus musculus)	BDBM50103555 (CHEMBL3358002) Show SMILES C[C@@H]1CN(CCN1c1ncc(OCc2ccc(OS(C)(=O)=O)cc2F)cn1)c1nnc(o1)C(F)(F)F |r| Show InChI InChI=1S/C20H20F4N6O5S/c1-12-10-29(19-28-27-17(34-19)20(22,23)24)5-6-30(12)18-25-8-15(9-26-18)33-11-13-3-4-14(7-16(13)21)35-36(2,31)32/h3-4,7-9,12H,5-6,10-11H2,1-2H3/t12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assay				J Med Chem 57: 8984-98 (2014) BindingDB Entry DOI: 10.7270/Q29G5PK1
					More data for this Ligand-Target Pair