BDBM50103560 CHEMBL3357997

SMILES: C[C@@H]1CN(CCN1c1ncc(OCc2ccc(cc2)S(C)(=O)=O)cn1)c1nnc(o1)C(F)(F)F

InChI Key: InChIKey=OKBIYBZBOXQZAS-CYBMUJFWSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103560   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50103560 (CHEMBL3357997) Show SMILES C[C@@H]1CN(CCN1c1ncc(OCc2ccc(cc2)S(C)(=O)=O)cn1)c1nnc(o1)C(F)(F)F |r| Show InChI InChI=1S/C20H21F3N6O4S/c1-13-11-28(19-27-26-17(33-19)20(21,22)23)7-8-29(13)18-24-9-15(10-25-18)32-12-14-3-5-16(6-4-14)34(2,30)31/h3-6,9-10,13H,7-8,11-12H2,1-2H3/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp based electrophysiology method				J Med Chem 57: 8984-98 (2014) BindingDB Entry DOI: 10.7270/Q29G5PK1
					More data for this Ligand-Target Pair
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50103560 (CHEMBL3357997) Show SMILES C[C@@H]1CN(CCN1c1ncc(OCc2ccc(cc2)S(C)(=O)=O)cn1)c1nnc(o1)C(F)(F)F |r| Show InChI InChI=1S/C20H21F3N6O4S/c1-13-11-28(19-27-26-17(33-19)20(21,22)23)7-8-29(13)18-24-9-15(10-25-18)32-12-14-3-5-16(6-4-14)34(2,30)31/h3-6,9-10,13H,7-8,11-12H2,1-2H3/t13-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	133	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assay				J Med Chem 57: 8984-98 (2014) BindingDB Entry DOI: 10.7270/Q29G5PK1
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Mus musculus)	BDBM50103560 (CHEMBL3357997) Show SMILES C[C@@H]1CN(CCN1c1ncc(OCc2ccc(cc2)S(C)(=O)=O)cn1)c1nnc(o1)C(F)(F)F |r| Show InChI InChI=1S/C20H21F3N6O4S/c1-13-11-28(19-27-26-17(33-19)20(21,22)23)7-8-29(13)18-24-9-15(10-25-18)32-12-14-3-5-16(6-4-14)34(2,30)31/h3-6,9-10,13H,7-8,11-12H2,1-2H3/t13-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	297	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assay				J Med Chem 57: 8984-98 (2014) BindingDB Entry DOI: 10.7270/Q29G5PK1
					More data for this Ligand-Target Pair