BDBM50103651 2-(3'-Amino-5-chloro-2-hydroxy-biphenyl-3-yl)-1H-benzoimidazole-5-carboxamidine::CHEMBL73737
SMILES: NC(=N)c1ccc2nc([nH]c2c1)-c1cc(Cl)cc(-c2cccc(N)c2)c1O
InChI Key: InChIKey=WLDWWFXJFODOTC-UHFFFAOYSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor III/Factor VIIa (fVIIa) (Homo sapiens (Human)) | BDBM50103651 (2-(3'-Amino-5-chloro-2-hydroxy-biphenyl-3-yl)-1H-b...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0780 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity for factor VIIa/TF | Bioorg Med Chem Lett 11: 2253-6 (2001) BindingDB Entry DOI: 10.7270/Q2XG9QD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urokinase-type plasminogen activator (Homo sapiens (Human)) | BDBM50103651 (2-(3'-Amino-5-chloro-2-hydroxy-biphenyl-3-yl)-1H-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity of the compound towards urokinase-type plasminogen activator (microPa) | Bioorg Med Chem Lett 11: 2253-6 (2001) BindingDB Entry DOI: 10.7270/Q2XG9QD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50103651 (2-(3'-Amino-5-chloro-2-hydroxy-biphenyl-3-yl)-1H-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity of the compound towards Coagulation factor X | Bioorg Med Chem Lett 11: 2253-6 (2001) BindingDB Entry DOI: 10.7270/Q2XG9QD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50103651 (2-(3'-Amino-5-chloro-2-hydroxy-biphenyl-3-yl)-1H-b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity of the compound towards Plasmin | Bioorg Med Chem Lett 11: 2253-6 (2001) BindingDB Entry DOI: 10.7270/Q2XG9QD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50103651 (2-(3'-Amino-5-chloro-2-hydroxy-biphenyl-3-yl)-1H-b...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity of the compound towards Coagulation factor II | Bioorg Med Chem Lett 11: 2253-6 (2001) BindingDB Entry DOI: 10.7270/Q2XG9QD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-1 (Homo sapiens (Human)) | BDBM50103651 (2-(3'-Amino-5-chloro-2-hydroxy-biphenyl-3-yl)-1H-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity of the compound towards Trypsin | Bioorg Med Chem Lett 11: 2253-6 (2001) BindingDB Entry DOI: 10.7270/Q2XG9QD9 | |||||||||||
More data for this Ligand-Target Pair |