BDBM50103830 8-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3,4-dihydro-2H-benzo[1,4]oxazine::CHEMBL310048

SMILES: C(N1CCN(CC1)c1cccc2NCCOc12)c1cccc(c1)-c1ccccc1

InChI Key: InChIKey=FNEYDYBEZUNJRD-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50103830   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50103830 (8-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3,4-dihyd...) Show SMILES C(N1CCN(CC1)c1cccc2NCCOc12)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C25H27N3O/c1-2-7-21(8-3-1)22-9-4-6-20(18-22)19-27-13-15-28(16-14-27)24-11-5-10-23-25(24)29-17-12-26-23/h1-11,18,26H,12-17,19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D2 determined using [3H]-spiperone				Bioorg Med Chem Lett 11: 2345-9 (2001) BindingDB Entry DOI: 10.7270/Q2RR1XH9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50103830 (8-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3,4-dihyd...) Show SMILES C(N1CCN(CC1)c1cccc2NCCOc12)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C25H27N3O/c1-2-7-21(8-3-1)22-9-4-6-20(18-22)19-27-13-15-28(16-14-27)24-11-5-10-23-25(24)29-17-12-26-23/h1-11,18,26H,12-17,19H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 1A receptor determined using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 11: 2345-9 (2001) BindingDB Entry DOI: 10.7270/Q2RR1XH9
					More data for this Ligand-Target Pair