BDBM50103941 2-Isopropoxy-3-(4-{2-[5-(3-trifluoromethyl-phenyl)-[1,2,4]oxadiazol-3-yl]-ethoxy}-phenyl)-propionic acid::2-isopropoxy-3-(4-(2-(5-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-3-yl)ethoxy)phenyl)propanoic acid::CHEMBL80791
SMILES: CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2cccc(c2)C(F)(F)F)cc1)C(O)=O
InChI Key: InChIKey=CKRAIKBZLALRCB-UHFFFAOYSA-N
Data: 7 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50103941 (2-Isopropoxy-3-(4-{2-[5-(3-trifluoromethyl-phenyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Agonist activity against human Peroxisome proliferator activated receptor alpha receptor in CV-1 cell was determined | Bioorg Med Chem Lett 11: 2385-8 (2001) BindingDB Entry DOI: 10.7270/Q2CJ8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50103941 (2-Isopropoxy-3-(4-{2-[5-(3-trifluoromethyl-phenyl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Agonist activity against human Peroxisome proliferator activated receptor gamma receptor in CV-1 cell was determined | Bioorg Med Chem Lett 11: 2385-8 (2001) BindingDB Entry DOI: 10.7270/Q2CJ8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM50103941 (2-Isopropoxy-3-(4-{2-[5-(3-trifluoromethyl-phenyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Agonist activity against human PPAR delta receptor in CV-1 cell was determined | Bioorg Med Chem Lett 11: 2385-8 (2001) BindingDB Entry DOI: 10.7270/Q2CJ8CSF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50103941 (2-Isopropoxy-3-(4-{2-[5-(3-trifluoromethyl-phenyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | 5.00E+6 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at PPARalpha (unknown origin) | Citation and Details Article DOI: 10.1007/s00044-004-0110-y BindingDB Entry DOI: 10.7270/Q2DJ5JH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50103941 (2-Isopropoxy-3-(4-{2-[5-(3-trifluoromethyl-phenyl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research Curated by ChEMBL | Assay Description Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra... | Eur J Med Chem 43: 2784-91 (2008) Article DOI: 10.1016/j.ejmech.2008.01.017 BindingDB Entry DOI: 10.7270/Q2W095QK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM50103941 (2-Isopropoxy-3-(4-{2-[5-(3-trifluoromethyl-phenyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research Curated by ChEMBL | Assay Description Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra... | Eur J Med Chem 43: 2784-91 (2008) Article DOI: 10.1016/j.ejmech.2008.01.017 BindingDB Entry DOI: 10.7270/Q2W095QK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50103941 (2-Isopropoxy-3-(4-{2-[5-(3-trifluoromethyl-phenyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research Curated by ChEMBL | Assay Description Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra... | Eur J Med Chem 43: 2784-91 (2008) Article DOI: 10.1016/j.ejmech.2008.01.017 BindingDB Entry DOI: 10.7270/Q2W095QK | |||||||||||
More data for this Ligand-Target Pair |