null

SMILES: CC(C)C(=O)Nc1ccc(cc1)C1NC(=O)c2cccnc2N1C

InChI Key: InChIKey=HYCDNVMZCASXNO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50104282 (CHEMBL3593718) Show SMILES CC(C)C(=O)Nc1ccc(cc1)C1NC(=O)c2cccnc2N1C Show InChI InChI=1S/C18H20N4O2/c1-11(2)17(23)20-13-8-6-12(7-9-13)15-21-18(24)14-5-4-10-19-16(14)22(15)3/h4-11,15H,1-3H3,(H,20,23)(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of human TNKS2 (956 to 1161 and 873 to 1161) using 500 nM NAD substrate after 20 mins incubation by fluorescence assay				Bioorg Med Chem 23: 4139-49 (2015) Article DOI: 10.1016/j.bmc.2015.06.063 BindingDB Entry DOI: 10.7270/Q2W66NJ2
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50104282 (CHEMBL3593718) Show SMILES CC(C)C(=O)Nc1ccc(cc1)C1NC(=O)c2cccnc2N1C Show InChI InChI=1S/C18H20N4O2/c1-11(2)17(23)20-13-8-6-12(7-9-13)15-21-18(24)14-5-4-10-19-16(14)22(15)3/h4-11,15H,1-3H3,(H,20,23)(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of human TNKS2 (956 to 1161 and 873 to 1161) using 500 nM NAD substrate after 20 mins incubation by fluorescence assay				Bioorg Med Chem 23: 4139-49 (2015) Article DOI: 10.1016/j.bmc.2015.06.063 BindingDB Entry DOI: 10.7270/Q2W66NJ2
					More data for this Ligand-Target Pair