BDBM50104473 (R)-2-[(R)-1-{12-[(2-Chloro-phenoxy)-hydroxy-phosphoryloxy]-dodecylcarbamoyl}-2-(1H-indol-3-yl)-ethylcarbamoyl]-pyrrolidine-1-carboxylic acid tert-butyl ester; compound with triethyl-amine::CHEMBL86984

SMILES: CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl

InChI Key: InChIKey=BOIIFJMSIMAJLB-KKLWWLSJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50104473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50104473 ((R)-2-[(R)-1-{12-[(2-Chloro-phenoxy)-hydroxy-phosp...) Show SMILES CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C39H56ClN4O8P/c1-39(2,3)51-38(47)44-25-18-22-34(44)37(46)43-33(27-29-28-42-32-21-14-12-19-30(29)32)36(45)41-24-16-10-8-6-4-5-7-9-11-17-26-50-53(48,49)52-35-23-15-13-20-31(35)40/h12-15,19-21,23,28,33-34,42H,4-11,16-18,22,24-27H2,1-3H3,(H,41,45)(H,43,46)(H,48,49)/t33-,34-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibitory activity against telomerase extracted from HCT 116 cell lines				Bioorg Med Chem Lett 11: 2581-4 (2001) BindingDB Entry DOI: 10.7270/Q2XD10Z2
					More data for this Ligand-Target Pair