BDBM50104483 CHEMBL313009::Phosphoric acid 2-chloro-phenyl ester 6-(2-{1-[3-(3-methyl-indol-1-yl)-propyl]-1H-indol-3-yl}-acetylamino)-hexyl ester; compound with triethyl-amine

SMILES: Cc1cn(CCCn2cc(CC(=O)NCCCCCCOP(O)(=O)Oc3ccccc3Cl)c3ccccc23)c2ccccc12

InChI Key: InChIKey=CBQAXGJNHNBSFP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50104483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50104483 (CHEMBL313009 | Phosphoric acid 2-chloro-phenyl est...) Show SMILES Cc1cn(CCCn2cc(CC(=O)NCCCCCCOP(O)(=O)Oc3ccccc3Cl)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C34H39ClN3O5P/c1-26-24-37(31-16-7-4-13-28(26)31)20-12-21-38-25-27(29-14-5-8-17-32(29)38)23-34(39)36-19-10-2-3-11-22-42-44(40,41)43-33-18-9-6-15-30(33)35/h4-9,13-18,24-25H,2-3,10-12,19-23H2,1H3,(H,36,39)(H,40,41)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibitory activity against telomerase extracted from HCT 116 cell lines				Bioorg Med Chem Lett 11: 2581-4 (2001) BindingDB Entry DOI: 10.7270/Q2XD10Z2
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