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BDBM50104484 CHEMBL314057::Phosphoric acid 12-[(R)-2-benzoylamino-3-(1H-indol-3-yl)-propionylamino]-dodecyl ester 2-chloro-phenyl ester; compound with triethyl-amine

SMILES: OP(=O)(OCCCCCCCCCCCCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccccc1)Oc1ccccc1Cl

InChI Key: InChIKey=GJJUKCMQVCLKFW-MGBGTMOVSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50104484   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))		BDBM50104484
PNG
(CHEMBL314057 | Phosphoric acid 12-[(R)-2-benzoylam...)
Show SMILES OP(=O)(OCCCCCCCCCCCCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccccc1)Oc1ccccc1Cl
Show InChI InChI=1S/C36H45ClN3O6P/c37-31-21-13-15-23-34(31)46-47(43,44)45-25-17-8-6-4-2-1-3-5-7-16-24-38-36(42)33(40-35(41)28-18-10-9-11-19-28)26-29-27-39-32-22-14-12-20-30(29)32/h9-15,18-23,27,33,39H,1-8,16-17,24-26H2,(H,38,42)(H,40,41)(H,43,44)/t33-/m1/s1
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Similars
PubMed
n/an/a 7.30E+3n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines

Bioorg Med Chem Lett 11: 2581-4 (2001)


BindingDB Entry DOI: 10.7270/Q2XD10Z2
More data for this
Ligand-Target Pair