BDBM50104818 2-[2-Methoxy-5-(3-phenyl-propyl)-phenyl]-ethylamine::CHEMBL326565

SMILES: COc1ccc(CCCc2ccccc2)cc1CCN

InChI Key: InChIKey=KGGJBMCZLCJIHX-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50104818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50104818 (2-[2-Methoxy-5-(3-phenyl-propyl)-phenyl]-ethylamin...) Show SMILES COc1ccc(CCCc2ccccc2)cc1CCN Show InChI InChI=1S/C18H23NO/c1-20-18-11-10-16(14-17(18)12-13-19)9-5-8-15-6-3-2-4-7-15/h2-4,6-7,10-11,14H,5,8-9,12-13,19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat 5HT2A expressed in mouse NIH/3T3 cell membranes after 30 mins by scintillation counting method				J Med Chem 60: 2605-2628 (2017) Article DOI: 10.1021/acs.jmedchem.7b00085 BindingDB Entry DOI: 10.7270/Q2DJ5HWM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50104818 (2-[2-Methoxy-5-(3-phenyl-propyl)-phenyl]-ethylamin...) Show SMILES COc1ccc(CCCc2ccccc2)cc1CCN Show InChI InChI=1S/C18H23NO/c1-20-18-11-10-16(14-17(18)12-13-19)9-5-8-15-6-3-2-4-7-15/h2-4,6-7,10-11,14H,5,8-9,12-13,19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin as radioligand				J Med Chem 44: 3283-91 (2001) BindingDB Entry DOI: 10.7270/Q2MW2GFJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50104818 (2-[2-Methoxy-5-(3-phenyl-propyl)-phenyl]-ethylamin...) Show SMILES COc1ccc(CCCc2ccccc2)cc1CCN Show InChI InChI=1S/C18H23NO/c1-20-18-11-10-16(14-17(18)12-13-19)9-5-8-15-6-3-2-4-7-15/h2-4,6-7,10-11,14H,5,8-9,12-13,19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				J Med Chem 44: 3283-91 (2001) BindingDB Entry DOI: 10.7270/Q2MW2GFJ
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50104818 (2-[2-Methoxy-5-(3-phenyl-propyl)-phenyl]-ethylamin...) Show SMILES COc1ccc(CCCc2ccccc2)cc1CCN Show InChI InChI=1S/C18H23NO/c1-20-18-11-10-16(14-17(18)12-13-19)9-5-8-15-6-3-2-4-7-15/h2-4,6-7,10-11,14H,5,8-9,12-13,19H2,1H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand				J Med Chem 44: 3283-91 (2001) BindingDB Entry DOI: 10.7270/Q2MW2GFJ
					More data for this Ligand-Target Pair