null

SMILES: O=C(OCc1cccnc1)N1CCC2(CC1)N(CNC2=O)c1ccccc1

InChI Key: InChIKey=GZRBSUJJSIHKKU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50105073 (4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...) Show SMILES O=C(OCc1cccnc1)N1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C20H22N4O3/c25-18-20(24(15-22-18)17-6-2-1-3-7-17)8-11-23(12-9-20)19(26)27-14-16-5-4-10-21-13-16/h1-7,10,13H,8-9,11-12,14-15H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F-59000 Lille Curated by ChEMBL					Assay Description Binding affinity against delta-opiate receptor (human) using [3H]-DPDPE radioligand				J Med Chem 44: 3378-90 (2001) BindingDB Entry DOI: 10.7270/Q23X87B8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50105073 (4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...) Show SMILES O=C(OCc1cccnc1)N1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C20H22N4O3/c25-18-20(24(15-22-18)17-6-2-1-3-7-17)8-11-23(12-9-20)19(26)27-14-16-5-4-10-21-13-16/h1-7,10,13H,8-9,11-12,14-15H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
F-59000 Lille Curated by ChEMBL					Assay Description Binding affinity against opioid receptor kappa 1 by using [3H]U-69593 as radioligand				J Med Chem 44: 3391-401 (2001) BindingDB Entry DOI: 10.7270/Q2057GN9
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50105073 (4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...) Show SMILES O=C(OCc1cccnc1)N1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C20H22N4O3/c25-18-20(24(15-22-18)17-6-2-1-3-7-17)8-11-23(12-9-20)19(26)27-14-16-5-4-10-21-13-16/h1-7,10,13H,8-9,11-12,14-15H2,(H,22,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F-59000 Lille Curated by ChEMBL					Assay Description Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligand				J Med Chem 44: 3378-90 (2001) BindingDB Entry DOI: 10.7270/Q23X87B8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50105073 (4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...) Show SMILES O=C(OCc1cccnc1)N1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C20H22N4O3/c25-18-20(24(15-22-18)17-6-2-1-3-7-17)8-11-23(12-9-20)19(26)27-14-16-5-4-10-21-13-16/h1-7,10,13H,8-9,11-12,14-15H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
F-59000 Lille Curated by ChEMBL					Assay Description Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligand				J Med Chem 44: 3378-90 (2001) BindingDB Entry DOI: 10.7270/Q23X87B8
					More data for this Ligand-Target Pair