BDBM50105352 CHEMBL90864::N-(4-{3-[(S)-2-(3,4-Dichloro-phenyl)-2-hydroxy-ethyl]-3-methyl-ureido}-benzyl)-2,2-dimethyl-propionamide

SMILES: CN(C[C@@H](O)c1ccc(Cl)c(Cl)c1)C(=O)Nc1ccc(CNC(=O)C(C)(C)C)cc1

InChI Key: InChIKey=JTZAQLRMOKJWRW-LJQANCHMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50105352 (CHEMBL90864 | N-(4-{3-[(S)-2-(3,4-Dichloro-phenyl)...) Show SMILES CN(C[C@@H](O)c1ccc(Cl)c(Cl)c1)C(=O)Nc1ccc(CNC(=O)C(C)(C)C)cc1 Show InChI InChI=1S/C22H27Cl2N3O3/c1-22(2,3)20(29)25-12-14-5-8-16(9-6-14)26-21(30)27(4)13-19(28)15-7-10-17(23)18(24)11-15/h5-11,19,28H,12-13H2,1-4H3,(H,25,29)(H,26,30)/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity of the compound against platelet thrombin receptor				Bioorg Med Chem Lett 11: 2691-6 (2001) BindingDB Entry DOI: 10.7270/Q26Q1WJ1
					More data for this Ligand-Target Pair