BDBM50105585 2,3,4-Trihydroxy-benzoic acid 7-hydroxy-chroman-3-yl ester::CHEMBL96321
SMILES: Oc1ccc2CC(COc2c1)OC(=O)c1ccc(O)c(O)c1O
InChI Key: InChIKey=DKJUMQVLXFGLAB-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1) | BDBM50105585 (2,3,4-Trihydroxy-benzoic acid 7-hydroxy-chroman-3-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toledo Curated by ChEMBL | Assay Description Inhibitory concentration against polymerization in A17 double mutant HIV-1 RT using a template primer of poly rC/dG12-18 and [3H]dGTP | Bioorg Med Chem Lett 11: 2763-7 (2001) BindingDB Entry DOI: 10.7270/Q2X92BTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50105585 (2,3,4-Trihydroxy-benzoic acid 7-hydroxy-chroman-3-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.63E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toledo Curated by ChEMBL | Assay Description Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTP | Bioorg Med Chem Lett 11: 2763-7 (2001) BindingDB Entry DOI: 10.7270/Q2X92BTR | |||||||||||
More data for this Ligand-Target Pair |