BindingDB logo
myBDB logout

null

SMILES: COC(=O)c1sc(cc1NC(=O)Nc1ccc(C)s1)C(C)(C)C

InChI Key: InChIKey=SVXOJPZSTRVYFC-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105620   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAF proto-oncogene serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50105620
PNG
(5-tert-Butyl-3-[3-(5-methyl-thiophen-2-yl)-ureido]...)
Show SMILES COC(=O)c1sc(cc1NC(=O)Nc1ccc(C)s1)C(C)(C)C
Show InChI InChI=1S/C16H20N2O3S2/c1-9-6-7-12(22-9)18-15(20)17-10-8-11(16(2,3)4)23-13(10)14(19)21-5/h6-8H,1-5H3,(H2,17,18,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 3.70E+3n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against raf kinase.

Bioorg Med Chem Lett 11: 2775-8 (2001)


BindingDB Entry DOI: 10.7270/Q2NS0VD5
More data for this
Ligand-Target Pair