BDBM50105787 (R)-2-[Bis-(2-methoxy-ethyl)-amino]-butyric acid 2,6-dimethoxy-4-methyl-phenyl ester::2-[Bis-(2-methoxy-ethyl)-amino]-butyric acid 2,6-dimethoxy-4-methyl-phenyl ester::CHEMBL13254::ORG-24447
SMILES: CC[C@@H](N(CCOC)CCOC)C(=O)Oc1c(OC)cc(C)cc1OC
InChI Key: InChIKey=GKRFHHRXDUACIN-OAHLLOKOSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human)) | BDBM50105787 ((R)-2-[Bis-(2-methoxy-ethyl)-amino]-butyric acid 2...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a |
Organon Research Curated by ChEMBL | Assay Description GABA-modulatory action compound was evaluated on Oocytes expressing recombinant human alpha-1-beta-3-gamma-2L GABA A receptor at concentrations of >=... | J Med Chem 44: 3582-91 (2001) BindingDB Entry DOI: 10.7270/Q2KW5GRD | |||||||||||
More data for this Ligand-Target Pair |