BDBM50105822 3'-Amino-biphenyl-4-sulfonic acid (2-phenyl-2H-pyrazol-3-yl)-amide::CHEMBL333108

SMILES: Nc1cccc(c1)-c1ccc(cc1)S(=O)(=O)Nc1ccnn1-c1ccccc1

InChI Key: InChIKey=HFOVGZDAQJHROY-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50105822 (3'-Amino-biphenyl-4-sulfonic acid (2-phenyl-2H-pyr...) Show SMILES Nc1cccc(c1)-c1ccc(cc1)S(=O)(=O)Nc1ccnn1-c1ccccc1 Show InChI InChI=1S/C21H18N4O2S/c22-18-6-4-5-17(15-18)16-9-11-20(12-10-16)28(26,27)24-21-13-14-23-25(21)19-7-2-1-3-8-19/h1-15,24H,22H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris V Curated by ChEMBL					Assay Description Inhibitory effect on human recombinant liver cytochrome P450 2C9 expressed in yeast strain				J Med Chem 44: 3622-31 (2001) BindingDB Entry DOI: 10.7270/Q20Z72KC
					More data for this Ligand-Target Pair
Cytochrome P450 2C18 (Homo sapiens (Human))	BDBM50105822 (3'-Amino-biphenyl-4-sulfonic acid (2-phenyl-2H-pyr...) Show SMILES Nc1cccc(c1)-c1ccc(cc1)S(=O)(=O)Nc1ccnn1-c1ccccc1 Show InChI InChI=1S/C21H18N4O2S/c22-18-6-4-5-17(15-18)16-9-11-20(12-10-16)28(26,27)24-21-13-14-23-25(21)19-7-2-1-3-8-19/h1-15,24H,22H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris V Curated by ChEMBL					Assay Description Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strain				J Med Chem 44: 3622-31 (2001) BindingDB Entry DOI: 10.7270/Q20Z72KC
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50105822 (3'-Amino-biphenyl-4-sulfonic acid (2-phenyl-2H-pyr...) Show SMILES Nc1cccc(c1)-c1ccc(cc1)S(=O)(=O)Nc1ccnn1-c1ccccc1 Show InChI InChI=1S/C21H18N4O2S/c22-18-6-4-5-17(15-18)16-9-11-20(12-10-16)28(26,27)24-21-13-14-23-25(21)19-7-2-1-3-8-19/h1-15,24H,22H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris V Curated by ChEMBL					Assay Description Inhibitory effect on human recombinant liver cytochrome P450 2C19 expressed in yeast strain				J Med Chem 44: 3622-31 (2001) BindingDB Entry DOI: 10.7270/Q20Z72KC
					More data for this Ligand-Target Pair
Cytochrome P450 2C8 (Homo sapiens (Human))	BDBM50105822 (3'-Amino-biphenyl-4-sulfonic acid (2-phenyl-2H-pyr...) Show SMILES Nc1cccc(c1)-c1ccc(cc1)S(=O)(=O)Nc1ccnn1-c1ccccc1 Show InChI InChI=1S/C21H18N4O2S/c22-18-6-4-5-17(15-18)16-9-11-20(12-10-16)28(26,27)24-21-13-14-23-25(21)19-7-2-1-3-8-19/h1-15,24H,22H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris V Curated by ChEMBL					Assay Description Inhibitory effect on human recombinant liver Cytochrome P450 2C8 expressed in yeast strain				J Med Chem 44: 3622-31 (2001) BindingDB Entry DOI: 10.7270/Q20Z72KC
					More data for this Ligand-Target Pair