BDBM50105909 CHEMBL3597937
SMILES: CSc1cccc(Nc2nc(cs2)-c2cc(Cl)cs2)c1
InChI Key: InChIKey=QFGARQUESWFYGH-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50105909 (CHEMBL3597937) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a |
Istituto Giannina Gaslini Curated by ChEMBL | Assay Description Potentiator activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in iodine influx measured after 30... | Eur J Med Chem 99: 14-35 (2015) BindingDB Entry DOI: 10.7270/Q25M67GT | |||||||||||
More data for this Ligand-Target Pair |