null
SMILES: CCOC(=O)c1cc(on1)-c1csc(Nc2cccc(SC)c2)n1
InChI Key: InChIKey=XRKLRLHCOGLMLI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50105911 (CHEMBL3597886) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a |
Istituto Giannina Gaslini Curated by ChEMBL | Assay Description Potentiator activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in iodine influx measured after 30... | Eur J Med Chem 99: 14-35 (2015) BindingDB Entry DOI: 10.7270/Q25M67GT | |||||||||||
More data for this Ligand-Target Pair |