BDBM50105912 CHEMBL3133762

SMILES: Nc1nccc(n1)-c1cn(C(=O)N2CCOCC2)c2ccc(Br)cc12

InChI Key: InChIKey=PTQHCVXFSMUUIH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-phosphorylation regulated kinase 3 (Homo sapiens (Human))	BDBM50105912 (CHEMBL3133762) Show SMILES Nc1nccc(n1)-c1cn(C(=O)N2CCOCC2)c2ccc(Br)cc12 Show InChI InChI=1S/C17H16BrN5O2/c18-11-1-2-15-12(9-11)13(14-3-4-20-16(19)21-14)10-23(15)17(24)22-5-7-25-8-6-22/h1-4,9-10H,5-8H2,(H2,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
India; Academy of Scientific& Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Inhibition of Dyrk3 (unknown origin) using Woodtide as substrate after 30 mins by P81 membrane assay in presence of [33P]-g-ATP				Bioorg Med Chem Lett 25: 2948-52 (2015) BindingDB Entry DOI: 10.7270/Q21V5GR3
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 2 (Homo sapiens (Human))	BDBM50105912 (CHEMBL3133762) Show SMILES Nc1nccc(n1)-c1cn(C(=O)N2CCOCC2)c2ccc(Br)cc12 Show InChI InChI=1S/C17H16BrN5O2/c18-11-1-2-15-12(9-11)13(14-3-4-20-16(19)21-14)10-23(15)17(24)22-5-7-25-8-6-22/h1-4,9-10H,5-8H2,(H2,19,20,21)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
India; Academy of Scientific& Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Inhibition of Dyrk2 (unknown origin) using Woodtide as substrate after 30 mins by P81 membrane assay in presence of [33P]-g-ATP				Bioorg Med Chem Lett 25: 2948-52 (2015) BindingDB Entry DOI: 10.7270/Q21V5GR3
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50105912 (CHEMBL3133762) Show SMILES Nc1nccc(n1)-c1cn(C(=O)N2CCOCC2)c2ccc(Br)cc12 Show InChI InChI=1S/C17H16BrN5O2/c18-11-1-2-15-12(9-11)13(14-3-4-20-16(19)21-14)10-23(15)17(24)22-5-7-25-8-6-22/h1-4,9-10H,5-8H2,(H2,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
India; Academy of Scientific& Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Inhibition of Dyrk1A (unknown origin) using Woodtide as substrate after 30 mins by P81 membrane assay in presence of [33P]-g-ATP				Bioorg Med Chem Lett 25: 2948-52 (2015) BindingDB Entry DOI: 10.7270/Q21V5GR3
					More data for this Ligand-Target Pair