BDBM50105913 CHEMBL3597991

SMILES: c1ncc(s1)-c1cc(cs1)-c1cccnc1

InChI Key: InChIKey=WNKQZLFWZLQFOH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50105913 (CHEMBL3597991) Show SMILES c1ncc(s1)-c1cc(cs1)-c1cccnc1 Show InChI InChI=1S/C12H8N2S2/c1-2-9(5-13-3-1)10-4-11(15-7-10)12-6-14-8-16-12/h1-8H	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
India; Academy of Scientific& Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Inhibition of human recombinant His6-tagged Dyrk1A expressed in Escherichia coli using Woodtide as substrate after 15 mins by P81 membrane assay in p...				Bioorg Med Chem Lett 25: 2948-52 (2015) BindingDB Entry DOI: 10.7270/Q21V5GR3
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 2 (Homo sapiens (Human))	BDBM50105913 (CHEMBL3597991) Show SMILES c1ncc(s1)-c1cc(cs1)-c1cccnc1 Show InChI InChI=1S/C12H8N2S2/c1-2-9(5-13-3-1)10-4-11(15-7-10)12-6-14-8-16-12/h1-8H	PDB MMDB NCI pathway KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
India; Academy of Scientific& Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-fused Dyrk2 expressed in Escherichia coli using Woodtide as substrate after 15 mins by P81 membrane assay in pres...				Bioorg Med Chem Lett 25: 2948-52 (2015) BindingDB Entry DOI: 10.7270/Q21V5GR3
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-regulated kinases 1B (Homo sapiens (Human))	BDBM50105913 (CHEMBL3597991) Show SMILES c1ncc(s1)-c1cc(cs1)-c1cccnc1 Show InChI InChI=1S/C12H8N2S2/c1-2-9(5-13-3-1)10-4-11(15-7-10)12-6-14-8-16-12/h1-8H	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
India; Academy of Scientific& Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Inhibition of human recombinant Dyrk1B using Woodtide as substrate after 15 mins by P81 membrane assay in presence of [33P]-g-ATP				Bioorg Med Chem Lett 25: 2948-52 (2015) BindingDB Entry DOI: 10.7270/Q21V5GR3
					More data for this Ligand-Target Pair