BDBM50106181 Biphenyl-4-carboxylic acid (3,3-dimethyl-butyl)-amide::CHEMBL125016
SMILES: CC(C)(C)CCNC(=O)c1ccc(cc1)-c1ccccc1
InChI Key: InChIKey=KKIJCHVXXASCHI-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Voltage-gated potassium channel subunit Kv7.1 (Cavia porcellus) | BDBM50106181 (Biphenyl-4-carboxylic acid (3,3-dimethyl-butyl)-am...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes | J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C | |||||||||||
More data for this Ligand-Target Pair |