BDBM50106267 CHEMBL126374::[2-(1-Benzenesulfonyl-5-methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimethyl-amine

SMILES: COc1ccc2n(c(C)c(CCN(C)C)c2c1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=DNOJEKLHKJAPCC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50106267 (CHEMBL126374 | [2-(1-Benzenesulfonyl-5-methoxy-2-m...) Show SMILES COc1ccc2n(c(C)c(CCN(C)C)c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H24N2O3S/c1-15-18(12-13-21(2)3)19-14-16(25-4)10-11-20(19)22(15)26(23,24)17-8-6-5-7-9-17/h5-11,14H,12-13H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity as displacement of [3H]-5-HT binding to 5-hydroxytryptamine 6 receptor in HeLa cells.				J Med Chem 44: 3881-95 (2001) BindingDB Entry DOI: 10.7270/Q2T72GRW
					More data for this Ligand-Target Pair