BDBM50106270 CHEMBL339741::{2-[5-Methoxy-1-(thiophene-2-sulfonyl)-1H-indol-3-yl]-ethyl}-dimethyl-amine

SMILES: COc1ccc2n(cc(CCN(C)C)c2c1)S(=O)(=O)c1cccs1

InChI Key: InChIKey=IPAXTAWQPQEGJN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50106270 (CHEMBL339741 | {2-[5-Methoxy-1-(thiophene-2-sulfon...) Show SMILES COc1ccc2n(cc(CCN(C)C)c2c1)S(=O)(=O)c1cccs1 Show InChI InChI=1S/C17H20N2O3S2/c1-18(2)9-8-13-12-19(24(20,21)17-5-4-10-23-17)16-7-6-14(22-3)11-15(13)16/h4-7,10-12H,8-9H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity as displacement of [3H]-5-HT binding to 5-hydroxytryptamine 6 receptor in HeLa cells.				J Med Chem 44: 3881-95 (2001) BindingDB Entry DOI: 10.7270/Q2T72GRW
					More data for this Ligand-Target Pair