Found 4 hits for monomerid = 50106347 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50106347
(CHEMBL3596367)Show SMILES Cl.[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC(F)(F)F)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2ccccc12)ccc3O |r,TLB:31:6:19:10.17.16,4:5:19:10.17.16| Show InChI InChI=1S/C24H21F3N2O3.ClH/c25-24(26,27)11-29-8-7-22-18-12-5-6-16(30)20(18)32-21(22)19-14(10-23(22,31)17(29)9-12)13-3-1-2-4-15(13)28-19;/h1-6,17,21,28,30-31H,7-11H2;1H/t17-,21+,22+,23-;/m1./s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 134 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from human DOR expressed in CHO cells |
Bioorg Med Chem Lett 25: 2927-30 (2015)
BindingDB Entry DOI: 10.7270/Q28C9Z0W |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50106347
(CHEMBL3596367)Show SMILES Cl.[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC(F)(F)F)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2ccccc12)ccc3O |r,TLB:31:6:19:10.17.16,4:5:19:10.17.16| Show InChI InChI=1S/C24H21F3N2O3.ClH/c25-24(26,27)11-29-8-7-22-18-12-5-6-16(30)20(18)32-21(22)19-14(10-23(22,31)17(29)9-12)13-3-1-2-4-15(13)28-19;/h1-6,17,21,28,30-31H,7-11H2;1H/t17-,21+,22+,23-;/m1./s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from human KOR expressed in CHO cells |
Bioorg Med Chem Lett 25: 2927-30 (2015)
BindingDB Entry DOI: 10.7270/Q28C9Z0W |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50106347
(CHEMBL3596367)Show SMILES Cl.[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC(F)(F)F)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2ccccc12)ccc3O |r,TLB:31:6:19:10.17.16,4:5:19:10.17.16| Show InChI InChI=1S/C24H21F3N2O3.ClH/c25-24(26,27)11-29-8-7-22-18-12-5-6-16(30)20(18)32-21(22)19-14(10-23(22,31)17(29)9-12)13-3-1-2-4-15(13)28-19;/h1-6,17,21,28,30-31H,7-11H2;1H/t17-,21+,22+,23-;/m1./s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from human MOR expressed in CHO cells |
Bioorg Med Chem Lett 25: 2927-30 (2015)
BindingDB Entry DOI: 10.7270/Q28C9Z0W |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50106347
(CHEMBL3596367)Show SMILES Cl.[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC(F)(F)F)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2ccccc12)ccc3O |r,TLB:31:6:19:10.17.16,4:5:19:10.17.16| Show InChI InChI=1S/C24H21F3N2O3.ClH/c25-24(26,27)11-29-8-7-22-18-12-5-6-16(30)20(18)32-21(22)19-14(10-23(22,31)17(29)9-12)13-3-1-2-4-15(13)28-19;/h1-6,17,21,28,30-31H,7-11H2;1H/t17-,21+,22+,23-;/m1./s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 46 | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human DOR expressed in CHO cell membranes by [35S]GTPgammaS binding assay |
Bioorg Med Chem Lett 25: 2927-30 (2015)
BindingDB Entry DOI: 10.7270/Q28C9Z0W |
More data for this
Ligand-Target Pair | |
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