BDBM50106508 7-[2-(3,5-Dibromo-4-hydroxy-phenyl)-ethylamino]-quinoline-5,8-dione::CHEMBL336095
SMILES: Oc1cc(N=CCc2cc(Br)c(O)c(Br)c2)c(O)c2ncccc12
InChI Key: InChIKey=NKWFSWJBTHPLIV-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Dual specificity protein phosphatase (VHR) (Homo sapiens (Human)) | BDBM50106508 (7-[2-(3,5-Dibromo-4-hydroxy-phenyl)-ethylamino]-qu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibitory Activity against Recombinant Human VHR | J Med Chem 44: 4042-9 (2001) BindingDB Entry DOI: 10.7270/Q2X34WR5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ezrin (Homo sapiens (Human)) | BDBM50106508 (7-[2-(3,5-Dibromo-4-hydroxy-phenyl)-ethylamino]-qu...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a |
George Mason University Curated by ChEMBL | Assay Description Binding affinity to recombinant ezrin (unknown origin) by surface plasmon resonance spectrometry | Bioorg Med Chem 22: 478-87 (2013) Article DOI: 10.1016/j.bmc.2013.11.003 BindingDB Entry DOI: 10.7270/Q21Z45WT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-tyrosine phosphatase 1B (Homo sapiens (Human)) | BDBM50106508 (7-[2-(3,5-Dibromo-4-hydroxy-phenyl)-ethylamino]-qu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibitory Activity against Recombinant Human PTP1 | J Med Chem 44: 4042-9 (2001) BindingDB Entry DOI: 10.7270/Q2X34WR5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity phosphatase Cdc25B (Homo sapiens (Human)) | BDBM50106508 (7-[2-(3,5-Dibromo-4-hydroxy-phenyl)-ethylamino]-qu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human cell division cycle 25B | J Med Chem 44: 4042-9 (2001) BindingDB Entry DOI: 10.7270/Q2X34WR5 | |||||||||||
More data for this Ligand-Target Pair |