BDBM50106547 7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-but-1-enyl)-cyclopentyl]-hept-5-enoic acid::CHEMBL334398::PGF2Alpha,16-Phenoxy
SMILES: O[C@@H](COc1ccccc1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
InChI Key: InChIKey=FAPQZCFUFGJPFI-UEAHRUCRSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PTGFR (BOVINE) | BDBM50106547 (7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-but-1-enyl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alcon Laboratories Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 286: 1094-102 (1998) BindingDB Entry DOI: 10.7270/Q2KK99BC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human)) | BDBM50106547 (7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-but-1-enyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Functional activity in RAT-1 cells, transiently transfected with human prostaglandin EP1 receptor | J Med Chem 44: 4157-69 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NNP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor (Homo sapiens (Human)) | BDBM50106547 (7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-but-1-enyl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 186 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Functional activity in RAT-1 cells, transiently transfected with human prostaglandin EP3 receptor | J Med Chem 44: 4157-69 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NNP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50106547 (7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-but-1-enyl...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description In vitro binding of the compound at FP human prostaglandin receptor using [3H]-PGF-2 alpha as radioligand | J Med Chem 44: 4157-69 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NNP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid TP receptor (Homo sapiens (Human)) | BDBM50106547 (7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-but-1-enyl...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Functional activity in RAT-1 cells, transiently transfected with human prostaglandin TP receptor | J Med Chem 44: 4157-69 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NNP | |||||||||||
More data for this Ligand-Target Pair |