null
SMILES: Cn1cc(Cc2cn(CCCC(=O)NCc3ccc(cc3)-c3ccccc3)c(SCc3ccc(F)cc3)nc2=O)cn1
InChI Key: InChIKey=DTACIDVDQARVID-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-activating factor acetylhydrolase (Homo sapiens (Human)) | BDBM50107484 (CHEMBL150823 | N-Biphenyl-4-ylmethyl-4-[2-(4-fluor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human Lp-PLA2 (Lp-PLA2). | Bioorg Med Chem Lett 12: 51-5 (2001) BindingDB Entry DOI: 10.7270/Q2862FR5 | |||||||||||
More data for this Ligand-Target Pair |