BDBM50107530 4-[4-(5-Chloro-thiophen-2-yl)-2-methyl-oxazol-5-yl]-benzenesulfonamide::CHEMBL350422
SMILES: Cc1nc(-c2ccc(Cl)s2)c(o1)-c1ccc(cc1)S(N)(=O)=O
InChI Key: InChIKey=RGANEMJXHWAHQI-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclooxygenase (Homo sapiens (Human)) | BDBM50107530 (4-[4-(5-Chloro-thiophen-2-yl)-2-methyl-oxazol-5-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzyme | Bioorg Med Chem Lett 12: 65-8 (2001) BindingDB Entry DOI: 10.7270/Q24F1Q1V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human)) | BDBM50107530 (4-[4-(5-Chloro-thiophen-2-yl)-2-methyl-oxazol-5-yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1 | Bioorg Med Chem Lett 12: 65-8 (2001) BindingDB Entry DOI: 10.7270/Q24F1Q1V | |||||||||||
More data for this Ligand-Target Pair |