BDBM50107571 (R)-2-Biphenyl-4-ylmethyl-N*4*-hydroxy-N*1*-((1S,2R)-2-hydroxy-indan-1-yl)-succinamide::CHEMBL8702

SMILES: ONC(=O)C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12

InChI Key: InChIKey=WHHWDHNQTWOJFL-PFATUAPWSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50107571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50107571 ((R)-2-Biphenyl-4-ylmethyl-N*4*-hydroxy-N*1*-((1S,2...) Show SMILES ONC(=O)C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 Show InChI InChI=1S/C26H26N2O4/c29-23-15-20-8-4-5-9-22(20)25(23)27-26(31)21(16-24(30)28-32)14-17-10-12-19(13-11-17)18-6-2-1-3-7-18/h1-13,21,23,25,29,32H,14-16H2,(H,27,31)(H,28,30)/t21-,23-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Company Curated by ChEMBL					Assay Description Binding affinity for human gelatinase A (MMP-2)				Bioorg Med Chem Lett 12: 101-4 (2001) BindingDB Entry DOI: 10.7270/Q2R49Q1C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50107571 ((R)-2-Biphenyl-4-ylmethyl-N*4*-hydroxy-N*1*-((1S,2...) Show SMILES ONC(=O)C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 Show InChI InChI=1S/C26H26N2O4/c29-23-15-20-8-4-5-9-22(20)25(23)27-26(31)21(16-24(30)28-32)14-17-10-12-19(13-11-17)18-6-2-1-3-7-18/h1-13,21,23,25,29,32H,14-16H2,(H,27,31)(H,28,30)/t21-,23-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Company Curated by ChEMBL					Assay Description Binding affinity for human gelatinase B (MMP-9)				Bioorg Med Chem Lett 12: 101-4 (2001) BindingDB Entry DOI: 10.7270/Q2R49Q1C
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50107571 ((R)-2-Biphenyl-4-ylmethyl-N*4*-hydroxy-N*1*-((1S,2...) Show SMILES ONC(=O)C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 Show InChI InChI=1S/C26H26N2O4/c29-23-15-20-8-4-5-9-22(20)25(23)27-26(31)21(16-24(30)28-32)14-17-10-12-19(13-11-17)18-6-2-1-3-7-18/h1-13,21,23,25,29,32H,14-16H2,(H,27,31)(H,28,30)/t21-,23-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Company Curated by ChEMBL					Assay Description Binding affinity for neutrophil collagenase (MMP-1)				Bioorg Med Chem Lett 12: 101-4 (2001) BindingDB Entry DOI: 10.7270/Q2R49Q1C
					More data for this Ligand-Target Pair