BDBM50107782 4'-Chloro-6-methyl-biphenyl-2-carboxylic acid (2-methanesulfonylamino-indan-5-yl)-amide::CHEMBL412375

SMILES: Cc1cccc(C(=O)Nc2ccc3CC(Cc3c2)NS(C)(=O)=O)c1-c1ccc(Cl)cc1

InChI Key: InChIKey=HVJUJYFSYHNRDU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apolipoprotein B-100 (Homo sapiens (Human))	BDBM50107782 (4'-Chloro-6-methyl-biphenyl-2-carboxylic acid (2-m...) Show SMILES Cc1cccc(C(=O)Nc2ccc3CC(Cc3c2)NS(C)(=O)=O)c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H23ClN2O3S/c1-15-4-3-5-22(23(15)16-6-9-19(25)10-7-16)24(28)26-20-11-8-17-12-21(14-18(17)13-20)27-31(2,29)30/h3-11,13,21,27H,12,14H2,1-2H3,(H,26,28)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Reasearch Curated by ChEMBL					Assay Description Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nM				J Med Chem 44: 4677-87 (2001) BindingDB Entry DOI: 10.7270/Q23F4NXH
					More data for this Ligand-Target Pair
Microsomal triglyceride transfer protein (Homo sapiens (Human))	BDBM50107782 (4'-Chloro-6-methyl-biphenyl-2-carboxylic acid (2-m...) Show SMILES Cc1cccc(C(=O)Nc2ccc3CC(Cc3c2)NS(C)(=O)=O)c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H23ClN2O3S/c1-15-4-3-5-22(23(15)16-6-9-19(25)10-7-16)24(28)26-20-11-8-17-12-21(14-18(17)13-20)27-31(2,29)30/h3-11,13,21,27H,12,14H2,1-2H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Reasearch Curated by ChEMBL					Assay Description In vitro inhibitory activity against MTP using MTP transfer assay				J Med Chem 44: 4677-87 (2001) BindingDB Entry DOI: 10.7270/Q23F4NXH
					More data for this Ligand-Target Pair