null

SMILES: COc1cccc(C(=O)Nc2ccc3CC(Cc3c2)NS(C)(=O)=O)c1-c1ccc(Cl)cc1

InChI Key: InChIKey=GKJVTZJLHFEZJH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107791   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microsomal triglyceride transfer protein large subunit (Homo sapiens (Human))	BDBM50107791 (4'-Chloro-6-methoxy-biphenyl-2-carboxylic acid (2-...) Show SMILES COc1cccc(C(=O)Nc2ccc3CC(Cc3c2)NS(C)(=O)=O)c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H23ClN2O4S/c1-31-22-5-3-4-21(23(22)15-6-9-18(25)10-7-15)24(28)26-19-11-8-16-12-20(14-17(16)13-19)27-32(2,29)30/h3-11,13,20,27H,12,14H2,1-2H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Reasearch Curated by ChEMBL					Assay Description In vitro inhibitory activity against MTP using MTP transfer assay				J Med Chem 44: 4677-87 (2001) BindingDB Entry DOI: 10.7270/Q23F4NXH
					More data for this Ligand-Target Pair
Apolipoprotein B-100 (Homo sapiens (Human))	BDBM50107791 (4'-Chloro-6-methoxy-biphenyl-2-carboxylic acid (2-...) Show SMILES COc1cccc(C(=O)Nc2ccc3CC(Cc3c2)NS(C)(=O)=O)c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H23ClN2O4S/c1-31-22-5-3-4-21(23(22)15-6-9-18(25)10-7-15)24(28)26-19-11-8-16-12-20(14-17(16)13-19)27-32(2,29)30/h3-11,13,20,27H,12,14H2,1-2H3,(H,26,28)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Reasearch Curated by ChEMBL					Assay Description Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nM				J Med Chem 44: 4677-87 (2001) BindingDB Entry DOI: 10.7270/Q23F4NXH
					More data for this Ligand-Target Pair