BDBM50107807 4-{5-[(6-Methyl-4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-indan-2-yl}-piperazine-1-carboxylic acid methyl ester::CHEMBL358768

SMILES: COC(=O)N1CCN(CC1)[C@@H]1Cc2ccc(NC(=O)c3cccc(C)c3-c3ccc(cc3)C(F)(F)F)cc2C1

InChI Key: InChIKey=NGBACBJFDKYOER-RUZDIDTESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apolipoprotein B-100 (Homo sapiens (Human))	BDBM50107807 (4-{5-[(6-Methyl-4'-trifluoromethyl-biphenyl-2-carb...) Show SMILES COC(=O)N1CCN(CC1)[C@@H]1Cc2ccc(NC(=O)c3cccc(C)c3-c3ccc(cc3)C(F)(F)F)cc2C1 Show InChI InChI=1S/C30H30F3N3O3/c1-19-4-3-5-26(27(19)20-6-9-23(10-7-20)30(31,32)33)28(37)34-24-11-8-21-17-25(18-22(21)16-24)35-12-14-36(15-13-35)29(38)39-2/h3-11,16,25H,12-15,17-18H2,1-2H3,(H,34,37)/t25-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Reasearch Curated by ChEMBL					Assay Description Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nM				J Med Chem 44: 4677-87 (2001) BindingDB Entry DOI: 10.7270/Q23F4NXH
					More data for this Ligand-Target Pair
Microsomal triglyceride transfer protein (Homo sapiens (Human))	BDBM50107807 (4-{5-[(6-Methyl-4'-trifluoromethyl-biphenyl-2-carb...) Show SMILES COC(=O)N1CCN(CC1)[C@@H]1Cc2ccc(NC(=O)c3cccc(C)c3-c3ccc(cc3)C(F)(F)F)cc2C1 Show InChI InChI=1S/C30H30F3N3O3/c1-19-4-3-5-26(27(19)20-6-9-23(10-7-20)30(31,32)33)28(37)34-24-11-8-21-17-25(18-22(21)16-24)35-12-14-36(15-13-35)29(38)39-2/h3-11,16,25H,12-15,17-18H2,1-2H3,(H,34,37)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Reasearch Curated by ChEMBL					Assay Description In vitro inhibitory activity against MTP using MTP transfer assay				J Med Chem 44: 4677-87 (2001) BindingDB Entry DOI: 10.7270/Q23F4NXH
					More data for this Ligand-Target Pair