BDBM50107811 CHEMBL142733::{5-[(4,6-Dimethyl-4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-indan-2-ylmethyl}-carbamic acid methyl ester

SMILES: COC(=O)NCC1Cc2ccc(NC(=O)c3cc(C)cc(C)c3-c3ccc(cc3)C(F)(F)F)cc2C1

InChI Key: InChIKey=QWPNUQHQVLSBQS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107811   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apolipoprotein B-100 (Homo sapiens (Human))	BDBM50107811 (CHEMBL142733 | {5-[(4,6-Dimethyl-4'-trifluoromethy...) Show SMILES COC(=O)NCC1Cc2ccc(NC(=O)c3cc(C)cc(C)c3-c3ccc(cc3)C(F)(F)F)cc2C1 Show InChI InChI=1S/C28H27F3N2O3/c1-16-10-17(2)25(19-4-7-22(8-5-19)28(29,30)31)24(11-16)26(34)33-23-9-6-20-12-18(13-21(20)14-23)15-32-27(35)36-3/h4-11,14,18H,12-13,15H2,1-3H3,(H,32,35)(H,33,34)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Reasearch Curated by ChEMBL					Assay Description Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nM				J Med Chem 44: 4677-87 (2001) BindingDB Entry DOI: 10.7270/Q23F4NXH
					More data for this Ligand-Target Pair
Microsomal triglyceride transfer protein (Homo sapiens (Human))	BDBM50107811 (CHEMBL142733 | {5-[(4,6-Dimethyl-4'-trifluoromethy...) Show SMILES COC(=O)NCC1Cc2ccc(NC(=O)c3cc(C)cc(C)c3-c3ccc(cc3)C(F)(F)F)cc2C1 Show InChI InChI=1S/C28H27F3N2O3/c1-16-10-17(2)25(19-4-7-22(8-5-19)28(29,30)31)24(11-16)26(34)33-23-9-6-20-12-18(13-21(20)14-23)15-32-27(35)36-3/h4-11,14,18H,12-13,15H2,1-3H3,(H,32,35)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Reasearch Curated by ChEMBL					Assay Description In vitro inhibitory activity against MTP using MTP transfer assay				J Med Chem 44: 4677-87 (2001) BindingDB Entry DOI: 10.7270/Q23F4NXH
					More data for this Ligand-Target Pair