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SMILES: OC1(CCN(CCOc2ccc(cc2)C#Cc2ccc(cn2)-c2ccc(Cl)cc2)CC1)C(F)(F)F

InChI Key: InChIKey=VNXUKSFLBZQILZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107832   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50107832
PNG
(CHEMBL3601009)
Show SMILES OC1(CCN(CCOc2ccc(cc2)C#Cc2ccc(cn2)-c2ccc(Cl)cc2)CC1)C(F)(F)F
Show InChI InChI=1S/C27H24ClF3N2O2/c28-23-7-4-21(5-8-23)22-6-10-24(32-19-22)9-1-20-2-11-25(12-3-20)35-18-17-33-15-13-26(34,14-16-33)27(29,30)31/h2-8,10-12,19,34H,13-18H2
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PubMed
n/an/a 6n/an/an/an/an/an/a



Boehringer Ingelheim Pharma GmbH& Co. KG

Curated by ChEMBL


Assay Description
Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method

Bioorg Med Chem Lett 25: 3264-9 (2015)


BindingDB Entry DOI: 10.7270/Q25D8TMB
More data for this
Ligand-Target Pair