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SMILES: CSc1cccc(Nc2nc(cs2)-c2cccs2)c1

InChI Key: InChIKey=SWQWDVFQCWRUJQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108301   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cystic fibrosis transmembrane conductance regulator


(Homo sapiens (Human))		BDBM50108301
PNG
(CHEMBL3597882)
Show SMILES CSc1cccc(Nc2nc(cs2)-c2cccs2)c1
Show InChI InChI=1S/C14H12N2S3/c1-17-11-5-2-4-10(8-11)15-14-16-12(9-19-14)13-6-3-7-18-13/h2-9H,1H3,(H,15,16)
PDB

UniProtKB/SwissProt

antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/an/a 8.50E+3n/an/an/an/a



Istituto Giannina Gaslini

Curated by ChEMBL


Assay Description
Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as iodide influx after 24 hrs by HS-YFP assay

Eur J Med Chem 99: 14-35 (2015)


BindingDB Entry DOI: 10.7270/Q25M67GT
More data for this
Ligand-Target Pair