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BDBM50108469 3-[4-Methoxy-3'-(3-pyridin-3-ylmethyl-ureido)-biphenyl-3-sulfonylamino]-3-phenyl-propionic acid::CHEMBL65656

SMILES: COc1ccc(cc1S(=O)(=O)NC(CC(O)=O)c1ccccc1)-c1cccc(NC(=O)NCc2cccnc2)c1

InChI Key: InChIKey=DQXKSLHFXHKCEX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108469   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin alpha-V/beta-3


(Homo sapiens (Human))		BDBM50108469
PNG
(3-[4-Methoxy-3'-(3-pyridin-3-ylmethyl-ureido)-biph...)
Show SMILES COc1ccc(cc1S(=O)(=O)NC(CC(O)=O)c1ccccc1)-c1cccc(NC(=O)NCc2cccnc2)c1
Show InChI InChI=1S/C29H28N4O6S/c1-39-26-13-12-23(16-27(26)40(37,38)33-25(17-28(34)35)21-8-3-2-4-9-21)22-10-5-11-24(15-22)32-29(36)31-19-20-7-6-14-30-18-20/h2-16,18,25,33H,17,19H2,1H3,(H,34,35)(H2,31,32,36)
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PubMed
 14n/an/an/an/an/an/an/an/a



Bayer AG

Curated by ChEMBL


Assay Description
In vitro activity in an vitronectin receptor (alpha v beta3) scintillation bead assay using 125-I labelled echistatin as a radioligand

Bioorg Med Chem Lett 12: 205-8 (2001)


BindingDB Entry DOI: 10.7270/Q27945T7
More data for this
Ligand-Target Pair