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SMILES: CSc1cccc(Nc2nc(cs2)-c2ccc3OCOc3c2)c1

InChI Key: InChIKey=HIOOCTUIDBSHTK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108496   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cystic fibrosis transmembrane conductance regulator


(Homo sapiens (Human))		BDBM50108496
PNG
(CHEMBL3597875)
Show SMILES CSc1cccc(Nc2nc(cs2)-c2ccc3OCOc3c2)c1
Show InChI InChI=1S/C17H14N2O2S2/c1-22-13-4-2-3-12(8-13)18-17-19-14(9-23-17)11-5-6-15-16(7-11)21-10-20-15/h2-9H,10H2,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/an/a 7.10E+4n/an/an/an/a



Istituto Giannina Gaslini

Curated by ChEMBL


Assay Description
Potentiator activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in iodine influx measured after 30...

Eur J Med Chem 99: 14-35 (2015)


BindingDB Entry DOI: 10.7270/Q25M67GT
More data for this
Ligand-Target Pair