BDBM50108511 5-(4-Methyl-pent-3-enyl)-3a,4,7,7a-tetrahydro-isobenzofuran-1,3-dione::CHEMBL85858
SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O
InChI Key: InChIKey=USHLVOCVVSTOQO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50108511 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108511
(5-(4-Methyl-pent-3-enyl)-3a,4,7,7a-tetrahydro-isob...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:6| Show InChI InChI=1S/C14H18O3/c1-9(2)4-3-5-10-6-7-11-12(8-10)14(16)17-13(11)15/h4,6,11-12H,3,5,7-8H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108511
(5-(4-Methyl-pent-3-enyl)-3a,4,7,7a-tetrahydro-isob...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:6| Show InChI InChI=1S/C14H18O3/c1-9(2)4-3-5-10-6-7-11-12(8-10)14(16)17-13(11)15/h4,6,11-12H,3,5,7-8H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.49E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description Binding affinity for human cloned 5-hydroxytryptamine 3 receptor |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |