BDBM50108575 3-(4-Iodo-benzenesulfonylamino)-N-(5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-propionamide::CHEMBL108502

SMILES: NS(=O)(=O)c1nnc(NC(=O)CCNS(=O)(=O)c2ccc(I)cc2)s1

InChI Key: InChIKey=CBNHHPMBIUENPL-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50108575 (3-(4-Iodo-benzenesulfonylamino)-N-(5-sulfamoyl-[1,...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNS(=O)(=O)c2ccc(I)cc2)s1 Show InChI InChI=1S/C11H12IN5O5S3/c12-7-1-3-8(4-2-7)25(21,22)14-6-5-9(18)15-10-16-17-11(23-10)24(13,19)20/h1-4,14H,5-6H2,(H2,13,19,20)(H,15,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Inhibitory effect on human Carbonic anhydrase II				J Med Chem 45: 312-20 (2002) BindingDB Entry DOI: 10.7270/Q2ZP46TZ
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50108575 (3-(4-Iodo-benzenesulfonylamino)-N-(5-sulfamoyl-[1,...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNS(=O)(=O)c2ccc(I)cc2)s1 Show InChI InChI=1S/C11H12IN5O5S3/c12-7-1-3-8(4-2-7)25(21,22)14-6-5-9(18)15-10-16-17-11(23-10)24(13,19)20/h1-4,14H,5-6H2,(H2,13,19,20)(H,15,16,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Inhibitory effect on bovine Carbonic anhydrase IV				J Med Chem 45: 312-20 (2002) BindingDB Entry DOI: 10.7270/Q2ZP46TZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50108575 (3-(4-Iodo-benzenesulfonylamino)-N-(5-sulfamoyl-[1,...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCNS(=O)(=O)c2ccc(I)cc2)s1 Show InChI InChI=1S/C11H12IN5O5S3/c12-7-1-3-8(4-2-7)25(21,22)14-6-5-9(18)15-10-16-17-11(23-10)24(13,19)20/h1-4,14H,5-6H2,(H2,13,19,20)(H,15,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Inhibitory effect on human carbonic anhydrase I				J Med Chem 45: 312-20 (2002) BindingDB Entry DOI: 10.7270/Q2ZP46TZ
					More data for this Ligand-Target Pair