BDBM50108710 4-(4-Benzenesulfonyl-piperidin-1-yl)-1-(4-fluoro-phenyl)-butan-1-one::CHEMBL343411

SMILES: Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=PNYKTOLTLVTHTA-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50108710 (4-(4-Benzenesulfonyl-piperidin-1-yl)-1-(4-fluoro-p...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H24FNO3S/c22-18-10-8-17(9-11-18)21(24)7-4-14-23-15-12-20(13-16-23)27(25,26)19-5-2-1-3-6-19/h1-3,5-6,8-11,20H,4,7,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Binding affinity for displacement of [3H]ketanserin to rat 5-hydroxytryptamine 2A receptor stably expressed in CHO cells				J Med Chem 45: 492-503 (2002) BindingDB Entry DOI: 10.7270/Q2KH0P27
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50108710 (4-(4-Benzenesulfonyl-piperidin-1-yl)-1-(4-fluoro-p...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H24FNO3S/c22-18-10-8-17(9-11-18)21(24)7-4-14-23-15-12-20(13-16-23)27(25,26)19-5-2-1-3-6-19/h1-3,5-6,8-11,20H,4,7,12-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Binding affinity for displacement of [3H]ketanserin to human 5-hydroxytryptamine 2A receptor stably expressed in CHO cells				J Med Chem 45: 492-503 (2002) BindingDB Entry DOI: 10.7270/Q2KH0P27
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50108710 (4-(4-Benzenesulfonyl-piperidin-1-yl)-1-(4-fluoro-p...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H24FNO3S/c22-18-10-8-17(9-11-18)21(24)7-4-14-23-15-12-20(13-16-23)27(25,26)19-5-2-1-3-6-19/h1-3,5-6,8-11,20H,4,7,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Binding affinity for displacement of [3H]spiperone to human dopamine D2 (hD2) receptors stably expressed in CHO cells				J Med Chem 45: 492-503 (2002) BindingDB Entry DOI: 10.7270/Q2KH0P27
					More data for this Ligand-Target Pair